Referring to his You character's penchant for baseball hats as a disguise, Penn chimed in noting "the hat doesn't help anymore." However, Domino, who is also a birth worker, assured that what matters is the effort.

"The willingness he had to try, that's all I ever want from a partner in any capacity—business, friendship," she explained, "I feel like that is what I noticed about Penn right away."

But after five years of marriage, Domino—who wed the Easy A actor in 2017—shared that for her, it's important to keep noticing new things about her husband.

"When I feel like I know everything about Penn, and ‘Ugh, Penn's just doing a Penn right now,' I'm stunted," she said. "In romantic relationships, you have to stay as curious about them as you did when you met them."

On the podcast the pair also reminisced about how they met—which was though a mutual friend—as Penn was coming off of his Gossip Girl years.