Definitions from Wiktionary (Edisto) ▸ noun:(historical) A subtribe of the now-extinct Cusabo, a Native American tribal group who lived in what is now South Carolina. ▸ noun:One of South Carolina's Sea Islands, the larger part of which lies in Charleston County, with its southern tip in Colleton County. ▸ noun:A free-flowing blackwater river in South Carolina, flowing from its sources in Saluda and Edgefield counties, to its Atlantic Ocean mouth at Edisto Beach. ▸ noun:An unincorporated community and census-designated place in Orangeburg County, South Carolina, United States. ▸ noun:(historical) A member of the Native American subtribe of South Carolina.Calisto, almanach, vestigium, rostro, Autolycus, courtesie, Curti, commissurotomy, tabella, sententiam, more... ▸ Words similar to Edisto ▸ Usage examples for Edisto